Polymer NCIs, categorized under Situation 6, are particularly popular due to their relatively straightforward application process. This article delves into why polymer ingredients are considered the easiest to apply for under the current regulatory framework, and outlines the specific requirements involve...

On May 31, 2024, the China National Institutes for Food and Drug Control (NIFDC) unveiled the Guidelines for Research and Determination of the Safe Use History of New Cosmetic Ingredients (Trial) (Draft for Comments) (the Safe Use History Guidelines) and the Guidelines for Research and Determination of the Safe Consumption History of New Cosmetic Ingredients (Trial) (Draft for Comments) (the Safe Consumption History Guidelines) for public consultation...

On December 1, 2023, NIFDC released the second draft of the Technical Guidelines for Determination and Research of New Cosmetic Ingredients (NCIs). The purpose of the Guidelines is to establish standardized guiding principles for the identification and research of New Cosmetic Ingredients. It offers comprehensive information on NCI categorization, as well as the research content of and naming requirements for NCIs.

The current landscape of NCI applications is segmented into six distinct situations. While all NCI applications necessitate thorough dossier preparation, testing requirements vary among different situations, which significantly impacts enterprise’s compliance cycle...

Characteristics of new cosmetic ingredients notified in China in 2023: 1) NCIs sources: chemical sources remain dominant; biotech ingredients and plant extracts are on the rise; 2) Use purpose: skin protectant, moisturizer and antioxidant account for more than half; 3) Notifiers: Chinese domestic enterprises account for 72.5%; 4) Future trends: the total number of NCI notifications is expected to grow, with a focus on ingredients that have already been allowed for use in cosmetics abroad and ingredients sourced from diverse fields.

Notification number: followed steady increase in 2022, the NCI notification number is expected to reach a new high in 2023; NCI sources: chemical and biotechnology sources still dominate; Use purpose: skin protectant, moisturizer and antioxidant account for more than half.

As revealed by China National Medical Products Administration’s (NMPA) database, Oligopeptide-215 from a Chinese company Shenzhen Winkey Pharmaceutical R&D Co., Ltd., has completed the new cosmetic ingredient (NCI) notification on June 14, 2022...

The first notified new cosmetic ingredient, Acetylneuraminic Acid, expanded its use purposes to anti-wrinkle agent, antioxidant, skin protectant, and moisturizer.

Detailed documentation requirements for cosmetic and new cosmetic ingredient (NCI) registration and notification are finalized. Imported general cosmetics can be exempt from animal testing from May 1, 2021 under certain conditions. Animal testing alternative method data for NCI registration/notification can be conditionally accepted.